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Foxx-Orenstein, Perform, FACG. Various studies attribute increased degrees of feminine sex hormones, progesterone particularly, with changes in GI motility in being pregnant. Another highlighted study found elevated degrees of progesterone accompanied by elevated intra-abdominal pressures from the enlarging uterus, may lower esophageal sphincter pressure adding to heartburn symptoms, probably the most reported complaints of pregnant women commonly.In the past year, drug manufacturers’ thirst for innovation coupled with small companies’ dwindling working capital to operate a vehicle merger and acquisition activity. At the top quality of the scale, consolidation among sector leaders created a few of the richest pharmaceutical mergers ever sold. 2010 promises to keep the cycle of acquisition as businesses seek ways to bolster their pipelines and portfolios. Smaller acquisitions are what we expect to see in the years ahead, said Jason Richardson, president of Cutting Edge Information. The blockbuster deals of days gone by year mean that some larger businesses will be integrating functions while buyers look for small, strategic deals that bulk up pipelines.